Model Based Drug Delivery for Anesthesia

نویسندگان

  • Pinky Dua
  • Vivek Dua
  • Efstratios N. Pistikopoulos
چکیده

In this work a compartmental model for delivery of three drugs (isoflurane, dopamine and sodium nitroprusside) for anesthesia is presented. The key feature of this model is that mean arterial pressure and unconsciousness of the patient can be simultaneously regulated. A number of dynamic simulation experiments are carried out for the validation of the model. Copyright © 2005 IFAC

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mathematical Analysis of Drug Release for Gastrointestinal Targeted Delivery Using β-Lactoglobulin Nanoparticle

To answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. In the present paper, controlled metal based drug (Pd(II) complex) release manner of β‑Lactoglobulin (β-LG) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

متن کامل

Synthesis and structural properties of Polyvinylpyrrolidone based nanocomposite hydrogels for isoniazid drug delivery

In this study, several examples of hydrogels and nanocomposite hydrogels based on PVP with different content of montmorillonite nanoclay were prepared. Then, the swelling of hydrogels and kinetics of drug delivery of hydrogel in an environment similar to the body (pH 7.4) were examined. The effect of nanoparticle different percentages on the hydrogel was clearly observed. Then kinetics of drug ...

متن کامل

Modification of Polyvinyl Alcohol via Atom Transfer Radical Polymerization for Targeted Drug Delivery Applications

In current study,a hydrogel based on biocompatible polymerwas prepared. The functionalization of polyvinyl alcohol (PVA)with epichlorohydrin(ECH) to produce epichlorohydrin-g-polyvinyl alcohol (PVA/ECH) as a suitable macroinitiator for atom transfer radical polymerization (ATRP) reaction was investigated.ThenN-vinyl pyrrolidone (NVP) waspolymerized on the surface of macroinitiatorin presence of...

متن کامل

Design and performance investigation of electrospun PVA nanofibers containing core-shell nanostructures for anticancer drug delivery

Objective: The purpose of this work was design and performance investigation of a nanocarrier based on magnetic nanofibers containing core-shell nanostructuresfor anticancerdrug delivery of daunorubicin (DAN) by measuring their drug release at different pH values. Methods: Fe3O4 nanoparticles and Fe3O4@SiO2core-shell nanostructures were synthesized through coprecipitation and Stöber methodresp...

متن کامل

Design of the optimal magnetic field in application of functionalized CNT-based drug delivery toward the cell membrane: Computational Analysis

Recently, Carbon Nano (CN) structures are widely used in medical applications, especially the detection and treatment of cancer disease. Among various types of CNs, Carbone Nano Tubes (CNTs) attracted many researchers' attention to consider them toward clinical application. Regarding the intrinsic structure of CNTs, they can be used widely in drug delivery applications. Functionalized CNTs and ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005